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All organisms are constantly exposed to chemicals that can not be used as a food and which could be harmful in the event of their getting into the cells, because they serve no metabolic function. These potentially dangerous substances are how to lose weight fast. Xenobiotics such as drugs, drugs, natural poisons and antibiotics are detoksyfikowane using specific enzyme-metabolic ksenobiotyczno. In humans they include oxidase cytochrome P450s [88], UDP-glukuronosyltransferaza [89] and glutathione S-transferase [90]. These enzymes act in three steps: oxidation of xenobiotic (phase I), its molecules attach to the hydrophilic groups (phase II) and removing it from the cell along with the water (in multicellular organisms can digest it later), a phase III. These reactions are important for sozology, which are the basis of biodegradation of hazardous substances and bioremediation of contaminated soils and groundwater [91]. The extraordinary diversity of microorganisms makes them able to handle almost any types of xenobiotics [92].
A related problem for aerobic organisms is oxidative stress [93]. Processes such as oxidative phosphorylation or disulfide bond formation during the construction of proteins causes formation of reactive oxygen species, such as hydrogen peroxide [94]. These oxidants, causing damage to structures such as proteins and nucleic acids are neutralized by antioxidants and enzymes: catalase and peroxidase [95] [96].
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